Technical Articles

The Klotho gene, named after the Greek goddess of fate who weaves the thread of life. This gene family includes three subtypes: alpha, beta, and gamma, among which beta Klotho has become a research focus in the field of life sciences due to its unique role in metabolic regulation. As a single transmembrane protein, it is mainly distributed in the liver and white adipose tissue, and regulates metabolic balance by participating in multiple signaling pathways, providing a new perspective for the treatment of metabolic diseases.