Technical Articles

Tau protein is a microtubule-associated protein predominantly found in neurons, playing a crucial role in maintaining cellular cytoskeletal stability and neuronal function. However, when Tau protein undergoes abnormal modifications (such as hyperphosphorylation), it forms neurofibrillary tangles (NFTs), which are the hallmark pathological features of Alzheimer's disease (AD) and other tauopathies.

Atopic dermatitis (AD) is a common chronic inflammatory skin disease characterized by intense pruritus and recurrent eczematous lesions. In recent years, with the deepening understanding of AD pathogenesis, scientists have discovered that various cytokines and signaling pathways play pivotal roles in the disease process, providing a theoretical basis for the development of novel therapeutic targets.