Technical Articles

B cell signaling

BAFF&APRIL Heterotrimer His Tag蛋白：解码B细胞存活的"双重信号"，自身免疫与淋巴瘤研究的关键钥匙

BAFF&APRIL Heterotrimer His Tag Protein: Decoding the "Dual Signals" of B Cell Survival, a Key to Autoimmunity and Lymphoma Research

2025-12-08

The BAFF&APRIL heterotrimeric protein is an innovative recombinant tool that precisely mimics the complex signaling environment in vivo. By fusing B-cell activating factor (BAFF/BLyS) and a proliferation-inducing ligand (APRIL) in a heterotrimeric form with a histidine tag, it provides an unprecedented high-fidelity platform for studying the synergistic mechanisms of abnormal B-cell activation, survival, and antibody production.

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Immunity/Inflamma
BAFF & APRIL heterotrimer
BAFF
APRIL
B cell signaling
autoimmune diseases
systemic lupus erythematosus

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