Technical Articles

BCL-XL/CRBN PROTAC Kit

BCL-XL/CRBN PROTAC试剂盒：推动肿瘤选择性蛋白降解疗法开发的标准化工具

BCL-XL/CRBN PROTAC Kit: A Standardized Tool for Advancing Tumor-Selective Protein Degradation Therapy Development

2026-01-19

Proteolysis Targeting Chimeras (PROTAC) is a revolutionary drug development platform that harnesses the cell's own ubiquitin-proteasome system to selectively degrade disease-causing proteins.

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Cancer
BCL-XL/CRBN PROTAC Kit
Tumor
Protein degradation

基于BCL-XL/CRBN PROTAC试剂盒开发的新型BCL-XL降解剂增强BCL-2抑制功能的研究

Study on Novel BCL-XL Degraders Developed Based on BCL-XL/CRBN PROTAC Kits to Enhance BCL-2 Inhibitory Function

2026-01-06

Evasion of apoptosis is a hallmark of cancer, often involving an imbalance between pro-apoptotic and anti-apoptotic proteins (such as BCL-2 family proteins).

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Cancer
BCL-XL/CRBN PROTAC Kit
Apoptosis evasion
Anti-apoptotic protein

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