Technical Articles

BTK/CRBN
PROTAC降解BTK的机理研究、分子设计及TR-FRET检测应用
Mechanism study, molecular design, and TR-FRET detection application of PROTAC-mediated BTK degradation
发布时间 2026-04-17
In 2001, the concept of PROTAC was first proposed, which involves using bifunctional ligands to specifically bind to target proteins while recruiting E3 ligases for ubiquitination, ultimately leading to the degradation of the target proteins.
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  • Drug Research
  • BTK/CRBN
  • TR-FRET Technology
  • PROTAC Technology
Total 1
  • 1
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