Technical Articles

CD3E&CD3D

Targeting key regulatory components of immune cell activation: Construction and application of CD3E&CD3D heterodimeric Fc fusion proteins

2026-02-11

The T cell antigen receptor is the key molecule mediating adaptive cellular immune responses, and its function relies on tight binding with the CD3 complex.

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Stem Cells
CD3E&CD3D
Immune cell activation
T cell antigen receptor

ITPRIPL1 as a novel inhibitory ligand of CD3ε in tumor immune escape: Mechanisms and targeting strategies

2026-02-10

The advent of tumor immunotherapy, particularly immune checkpoint blockade therapy, has significantly transformed the treatment landscape for various malignant tumors.

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Cancer
CD3E&CD3D
Tumor immunology
Malignant tumor

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