Technical Articles

Cancer.

VEGF165: The "Core Commander" of Angiogenesis, A Double-Edged Sword in Disease Treatment and Progression

2025-11-25

VEGF165 is the predominant isoform of vascular endothelial growth factor-A, hailed as the "master switch" of angiogenesis. It plays a central role in development, repair, and numerous disease processes by precisely regulating the formation of new blood vessels.

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Cancer
EGF165
Vascular endothelial growth factor
Angiogenesis
VEGFR2
Cancer.

IL-12: The "Strategic Commander" of the Immune System - A Dual Mission from Anti-Infection to Anti-Cancer

2025-11-23

IL-12 is a heterodimeric cytokine produced by antigen-presenting cells (such as dendritic cells and macrophages), composed of two subunits, p35 and p40, linked by disulfide bonds. It plays a central role in the initiation and regulation of immune responses.

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Cancer
IL-12
Infectious diseases
Cancer.

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