Technical Articles

Exercise is an important way to prevent and improve metabolic syndrome and other diseases, and its beneficial effects independent of weight changes suggest the involvement of humoral factors in regulating metabolic adaptation during exercise.

IL-17F (Interleukin-17F) is one of the six members (IL-17A to F) of the IL-17 cytokine family and shares the highest amino acid sequence homology with IL-17A (approximately 50%).

TGF-β2 (Transforming Growth Factor-β2) is a key member of the Transforming Growth Factor β (TGF-β) cytokine superfamily. As a pivotal pleiotropic regulator, TGF-β2 plays an indispensable and highly context-dependent role in embryonic development, tissue homeostasis, immune regulation, and various disease processes.

TSLP His Tag protein (Thymic Stromal Lymphopoietin) is a four-helix bundle cytokine that plays a critical role at epithelial barrier sites, regarded as the core "alarm initiator" for initiating type 2 immunity and allergic inflammation.

TSLP His Tag protein (Thymic Stromal Lymphopoietin) is a four-helix bundle cytokine that plays a critical role at epithelial barrier sites, regarded as the core "alarm initiator" for initiating type 2 immunity and allergic inflammation.

VEGF 120 protein (commonly referred to as VEGF-A₁₂₁ or VEGF-A₁₆₅, depending on the species nomenclature) is a key splice isoform of vascular endothelial growth factor A (VEGF-A) and serves as a pivotal soluble cytokine regulating both physiological and pathological angiogenesis.

The Human IL10/IL10RA Binding Kit is an advanced in vitro biophysical research toolkit specifically designed for the precise quantification and kinetic analysis of the binding interactions between interleukin-10 and its high-affinity receptor IL-10Rα.

IL-6 (Interleukin-6) is one of the most versatile and widely influential core members in the cytokine network. It serves not only as a primary inducer of the acute-phase response but also as a critical messenger linking innate and adaptive immunity, while regulating hematopoietic, metabolic, and neuroendocrine systems.

Interleukin-13 (IL-13) is a key effector cytokine in type II immune responses, sharing highly overlapping functions with IL-4 but exhibiting significant differences in target cells. The core role of IL-13 is not to initiate immune responses but to directly act on structural cells in tissues (e.g., epithelial cells, fibroblasts, smooth muscle cells), executing terminal effects such as mucus secretion, tissue fibrosis, and airway hyperresponsiveness. It serves as the central "executor" in the pathogenesis of allergic diseases and tissue repair/fibrosis processes, with its dysfunction directly leading to chronic pathological states characterized by tissue remodeling.

Interleukin-5 (IL-5) is a highly specialized cytokine primarily responsible for regulating the production, activation, recruitment, and survival of eosinophils. Unlike multifunctional cytokines such as IL-2 or IL-4, IL-5 has a relatively focused scope of action, serving as the central orchestrator of eosinophil-related immune responses. It plays a pivotal role in both anti-parasitic defense and the pathogenesis of allergic diseases.