Technical Articles

This article systematically elucidates the central role of fibroblast growth factor (FGF) family members in cell culture and the technical challenges posed by their thermal instability. It highlights the principles of thermally stable FGF technology in enhancing stability and bioactivity through protein engineering, and analyzes the unique application value of FGF-10 as a key member in organoid research.

FGF-10, fully known as fibroblast growth factor-10, is a member of the FGF-7 subfamily within the FGF family. One of its most notable features is that it primarily functions through a paracrine mechanism, meaning it is secreted by mesenchymal cells and acts on neighboring epithelial cells.