Technical Articles

FGF basic (also known as FGF2 or bFGF) is a key factor in maintaining the undifferentiated state of human pluripotent stem cells, including ESCs and iPSCs. It activates signaling pathways such as MAPK/ERK and PI3K/AKT by binding to its receptors, promoting cell survival, inhibiting apoptosis, and supporting sustained self-renewal of cells.