Technical Articles

FLT-3L, fully known as FMS-like tyrosine kinase 3 ligand, is also referred to as FLT3 ligand or Flt3L. It is a critical cytokine produced by bone marrow stromal cells, among others. Its primary function is to regulate the proliferation, differentiation, and survival of hematopoietic stem cells by binding to the FLT3 receptor on the cell surface and activating downstream signaling pathways.

FLT-3L (FMS like tyrosine kinase 3 ligand) is an important hematopoietic cytokine that plays a central role in the development, differentiation, and survival of innate immune cells, especially NK cells, by binding to FLT-3 receptors.

FLT-3 ligand (FLT-3 Ligand, FLT-3L) is a specific ligand of FLT-3, a member of the type III tyrosine kinase receptor (RTKIII) family, and plays a key role in the development of hematopoietic stem cells, differentiation of immune cells and maintenance of tissue homeostasis.