Technical Articles
Fibrotic Diseases
Activin A Protein: From Key Physiological Regulator to Novel Therapeutic Target
Activin A, a key member of the TGF-β superfamily, is a dimeric protein formed by two βA subunits linked via disulfide bonds. This critical signaling molecule plays a central role in physiological processes such as embryonic development, tissue repair, and immune regulation, but its dysregulation has also become a pivotal factor in the pathogenesis of various diseases.
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- Cancer
- Activin A protein
- TGF-β superfamily
- fibrotic diseases
- tumor progression
- muscle atrophy
Activin A: A Double-Edged Sword in Regulating Life Processes
Activin A is a secreted protein belonging to the transforming growth factor-β superfamily. Like other well-known family members such as TGF-β and BMPs, it plays a central role in cell growth, differentiation, and apoptosis.
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- Cancer
- Activin A protein
- TGF-β superfamily
- fibrotic diseases
- tumor progression
- muscle atrophy
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