Technical Articles
Follicular Helper T Cells (Tfh)
IL-21: The Immune System's "Versatile Coordinator" and the Double-Edged Sword in Disease Treatment
2025-12-03Interleukin-21 (IL-21) is a pleiotropic cytokine produced by activated T cells, serving as a central messenger in coordinating humoral immunity, cellular immunity, and immune tolerance. It plays a complex and critical role in promoting antibody production, cytotoxic cell activation, and immune regulation.
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- Cancer
- IL-21
- Interleukin-21
- Follicular Helper T Cells (Tfh)
- Germinal Center
- Autoimmune Diseases
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