Technical Articles

The luciferase reporter gene assay is a powerful tool widely used in biomedical research to quantitatively and real-timely monitor the activity of specific signaling pathways or the transcriptional level of genes in live cells or cell lysates.

In the intricate world of cells, DNA repair enzymes known as PARPs (Poly ADP-Ribose Polymerases) play a pivotal role. These enzymes are not only critical participants in DNA damage repair but also exert significant functions in processes such as apoptosis, gene transcription, and DNA synthesis. This article delves into the functions, mechanisms of action, and biomedical applications of DNA repair enzyme PARPs.