Technical Articles

重组人epo蛋白:一个「造血激素」为什么在血管与神经研究里也常被提到?
Recombinant Human EPO: Why a Hematopoietic Hormone Keeps Showing Up in Vascular and Neural Research
发布时间 2026-10-15
EPO is a four-helix-bundle glycoprotein hormone acting through the EPOR-JAK2/STAT5 axis. This article explains erythroid development, glycosylation-driven molecular-weight heterogeneity and non-hematopoietic activities in vascular and neural research
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  • Cancer
  • EPO
  • EPOR
  • JAK2
  • STAT5
  • erythroid progenitor
  • glycosylation
  • CHO expression
  • neuroprotection
  • UA040004
重组人mog蛋白:MOG(1-125) 胞外域,为何是 EAE 模型绕不开的诱导抗原?
Recombinant Human MOG (1-125): The EAE Inductive Antigen Explained
发布时间 2026-10-12
MOG (1-125) is the extracellular IgV domain of myelin oligodendrocyte glycoprotein. This article explains its truncation range, immunodominant epitopes, glycosylation effect, and the EAE induction workflow.
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  • Immunity/Inflamma
  • MOG
  • MOG 1-125
  • myelin oligodendrocyte glycoprotein
  • EAE
  • multiple sclerosis
  • IgV domain
  • glycosylation
  • UA010471
埃博拉病毒糖蛋白:从三聚体结构到膜融合的精密机制
Ebola Virus Glycoprotein: From Trimeric Structure to the Precise Mechanism of Membrane Fusion
发布时间 2025-12-09
The glycoprotein (GP) of the Ebola virus (Ebolavirus) is a key molecule in the viral infection process. This type I envelope glycoprotein not only mediates viral entry into host cells but also forms a "glycan shield" through complex glycosylation modifications to help the virus evade host immune surveillance.
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  • Immunity/Inflamma
  • Ebola virus
  • Glycoprotein
  • Trimeric structure
  • Glycosylation
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