Technical Articles

The growth hormone signaling pathway is a critical endocrine axis that regulates linear body growth, metabolic homeostasis, and tissue repair. The proper functioning of this pathway relies on the precise binding of growth hormone to its cell surface receptor and subsequent signal transduction.

Growth hormone plays a crucial role in growth, metabolism, and reproduction. Although rhGH therapy has significant benefits in approved indications, its application requires careful patient selection, enhanced monitoring, and a thorough understanding of potential risks. Future research is expected to further expand its clinical application value while emphasizing evidence-based and ethical use.

Growth hormone (GH), as a key protein hormone secreted by the anterior pituitary gland, plays an irreplaceable role in regulating the growth and development of the body, metabolic balance and immune function. This article will discuss the physiological functions, molecular regulatory mechanisms, signal transduction pathways and cutting-edge research directions of GH.