Technical Articles

Human CD3E/CD3G Heterodimer Protein

CD3E/CD3G异二聚体：TCR-CD3复合物的结构基础与抗体药物研发的关键靶点

CD3E/CD3G heterodimer: The structural basis of TCR-CD3 complex and a key target for antibody drug development

2026-07-28

This article systematically elucidates the molecular basis of CD3E and CD3G forming heterodimers, their core functions in the assembly and signal transduction of the TCR-CD3 complex, and analyzes the necessity of their heterodimeric conformation under physiological conditions as well as its decisive impact on therapeutic antibody recognition.

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Immunity/Inflamma
Human CD3E/CD3G Heterodimer Protein

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