Technical Articles

IL-1β:炎症的"点火器"与全身性疾病的核心推手
IL-1β: The "Igniter" of Inflammation and a Key Driver of Systemic Diseases
发布时间 2025-11-24
IL-1β (Interleukin-1β) is one of the most potent pro-inflammatory cytokines in the body and is regarded as the "initiating factor" of inflammatory responses. Its production requires a precise and complex activation mechanism.
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  • Immunity/Inflamma
  • IL-1β
  • interleukin-1β
  • inflammasome
  • NLRP3 inflammasome
  • caspase-1
  • autoinflammatory diseases
  • gout.
白细胞介素 - 1β 在肿瘤免疫调控中的双重作用及其治疗潜力
Dual Roles of Interleukin-1β in Tumor Immune Regulation and Its Therapeutic Potential
发布时间 2025-07-14
In the field of tumor immunology, the complex regulatory network of inflammation and immune response has always been a research hotspot. Interleukin-1 β (IL-1 β), as a key pro-inflammatory cytokine, plays a "double agent" role in the interaction between the immune system and the tumor microenvironment. On the one hand, IL-1 β activates anti-tumor immune mechanisms by inducing acute inflammatory responses, directly or indirectly killing cancer cells; On the other hand, under specific conditions, it may accelerate tumor progression by promoting angiogenesis, tumor cell proliferation, and other pathways. The duality of this function makes it a highly controversial and promising target in tumor immunotherapy research.
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  • Immunity/Inflamma
  • IL-1β
  • Inflammation
  • immune response
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