Technical Articles
IL-17A/IL-17RA
Structural and Functional Studies of the IL-17A/IL-17RA Signaling Pathway Based on TR-FRET Technology
In 1993, researchers first cloned cytotoxic T lymphocyte-associated antigen 8 from an activated mouse T lymphocyte cDNA library, later named IL-17A. The IL-17A gene showed no homology with other known cytokine families at the time but exhibited 57% homology with the T-cell-tropic herpesvirus gene 13.
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- Signaling Pathway
- TR-FRET Technology
- IL-17A/IL-17RA
- Autoimmune Disease
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