Technical Articles

IL-2 Protein

Site-specific PEGylation modification of IL-2 protein and its immunosuppressive effects study

2026-03-31

The IL-2 protein is a key cytokine for the survival and function of regulatory T cells. This protein selectively binds to the trimeric IL-2 receptor on the surface of regulatory T cells, preferentially activating them and making it an important candidate molecule for the treatment of autoimmune diseases.

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Immunity/Inflamma
IL-2 Protein
Regulatory T Cells
Immune-Mediated Diseases

Biological Characteristics and Clinical Applications of IL-2 Protein

2026-03-30

The IL-2 protein is a type I four α-helix bundle cytokine, primarily produced by conventional T cells following engagement of the T cell receptor and the co-stimulatory molecule CD28.

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Cell Biology
IL-2 Protein
Regulatory T Cells
Signal Transduction

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