Technical Articles

IL-21R

Innovative Strategy for Engineering IL-21 Receptor to Enhance the Efficacy of TCR-T Cells Against Hepatocellular Carcinoma

2026-02-10

Hepatocellular carcinoma is the most common primary liver cancer and has limited response to conventional therapies. Adoptive T cell therapies (such as TCR-T therapy) have shown significant efficacy in hematologic malignancies.

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Cancer
IL-21R
TCR-T cell
Hepatocellular carcinoma

Structure and function of interleukin-21 receptor (IL-21R)

2026-01-15

Interleukin-21 (IL-21) is a pleiotropic cytokine belonging to the γc-chain cytokine family, playing a central regulatory role in adaptive immunity and humoral immunity.

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Immunity/Inflamma
IL-21R
Adaptive immunity
Humoral immunity

Total 2

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