Technical Articles

探索IdeS酶:从机制到治疗的革命性蛋白酶
Exploring IdeS Enzyme: A Revolutionary Protease from Mechanism to Treatment
发布时间 2025-08-29
deS(IgG-degrading enzyme of Streptococcus pyogenes) It is a specific protease derived from Streptococcus pyogenes, also known as Imlifidase.
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  • Stem Cells
  • IdeS
IdeS 介导的 IgG 切割:一种克服 AAV 载体基因治疗中中和抗体障碍的新策略
IdeS-Mediated IgG Cleavage: A Novel Strategy to Overcome Neutralizing Antibody Barriers in AAV Vector Gene Therapy
发布时间 2025-07-09
Adeno-associated virus (AAV) vector gene therapy has become a transformative approach for treating monogenic diseases, including hemophilia, spinal muscular atrophy, and hereditary retinal diseases. Its excellent safety, low immunogenicity, and ability to mediate long-term transgenic expression make it a leading platform in this field.
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  • Drug Research
  • IdeS
  • AAV
  • NAbs
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