Technical Articles
IdeS
Exploring IdeS Enzyme: A Revolutionary Protease from Mechanism to Treatment
deS(IgG-degrading enzyme of Streptococcus pyogenes) It is a specific protease derived from Streptococcus pyogenes, also known as Imlifidase.
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- Stem Cells
- IdeS
IdeS-Mediated IgG Cleavage: A Novel Strategy to Overcome Neutralizing Antibody Barriers in AAV Vector Gene Therapy
Adeno-associated virus (AAV) vector gene therapy has become a transformative approach for treating monogenic diseases, including hemophilia, spinal muscular atrophy, and hereditary retinal diseases. Its excellent safety, low immunogenicity, and ability to mediate long-term transgenic expression make it a leading platform in this field.
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- Drug Research
- IdeS
- AAV
- NAbs
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