Technical Articles

Immune-Mediated Diseases

Advances in Research on the TNF-α Signaling Pathway and Autoimmune Diseases

2026-04-22

Tumor necrosis factor α is a key pro-inflammatory cytokine with extensive biological functions, playing a central role in immune regulation, inflammatory responses, apoptosis, and the maintenance of tissue homeostasis in both physiological and pathological processes.

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Immunity/Inflamma
TNF-α Protein
Signaling Pathway
Immune-Mediated Diseases

Site-specific PEGylation modification of IL-2 protein and its immunosuppressive effects study

2026-03-31

The IL-2 protein is a key cytokine for the survival and function of regulatory T cells. This protein selectively binds to the trimeric IL-2 receptor on the surface of regulatory T cells, preferentially activating them and making it an important candidate molecule for the treatment of autoimmune diseases.

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Immunity/Inflamma
IL-2 Protein
Regulatory T Cells
Immune-Mediated Diseases

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