Technical Articles

Myelin oligodendrocyte glycoprotein is a myelin protein specifically expressed on the surface of oligodendrocytes in the central nervous system, located in the outermost layer of the myelin sheath. It consists of 218 amino acids and belongs to the immunoglobulin superfamily.

Immunoglobulins are the core effector molecules of the body's adaptive immune response, produced by plasma cells derived from activated B lymphocytes.

Leukocyte immunoglobulin-like receptor B4 is an important inhibitory receptor member of the leukocyte immunoglobulin-like receptor family.

B-cell activating factor (BAFF, also known as BLyS) and a proliferation-inducing ligand (APRIL) are important members of the tumor necrosis factor ligand superfamily, playing a central role in the survival, maturation, and functional differentiation of B cells.

BTN1A1 (Butyrophilin Subfamily 1 Member A1) is a key member of the butyrophilin family, initially discovered in mammary epithelial cells during lactation, and is closely associated with the formation and secretion of milk fat globule membranes.

LILRs are a group of immune regulatory receptors expressed by a variety of hematopoietic cell types, including monocytes, macrophages, dendritic cells, granulocytes, natural killer (NK) cells, T cells and B cells.

Immunoglobulins (Ig) are key molecules in the animal immune system. They play a vital role in humoral immunity, helping the body to identify and eliminate foreign antigens.

MYD1 (Macrophage-Derived 1 protein), a member of the immunoglobulin superfamily, exhibits distinct structural features. Encoded by the SHPS1 gene, MYD1 comprises three functional domains: Extracellular domain: Three immunoglobulin-like V-type domains (IgV-IgV-IgC) enabling ligand recognition. Transmembrane domain: α-helical structure ensuring membrane localization. Intracellular domain: Immunoreceptor tyrosine-based inhibitory motif (ITIM) mediating signal transduction.