Technical Articles

Signal transducer and activator of transcription 6 is a key member of the JAK-STAT signaling pathway family, serving as a central effector for interleukin-4 and interleukin-13 signaling, and plays a decisive role in allergic responses, parasitic immunity, and shaping specific tumor microenvironments.

In the complex regulatory network of the tumor microenvironment (TME), cytokines act as key signaling molecules to mediate dynamic interactions between immune cells and non immune cells, profoundly affecting the occurrence and development of tumors.