Technical Articles

KRAS G12C & CRBN Binding Kit (GDP loaded)

Research Progress on Resistance Mechanisms and Counterstrategies of KRAS G12C Inhibitors

2026-03-02

The KRAS gene is one of the most frequently mutated oncogenes in cancer. Due to its protein structure lacking ideal drug-binding pockets and its extremely high affinity for GTP, KRAS mutations have long been considered an "undruggable" target.

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Cancer
KRAS G12C & CRBN Binding Kit (GDP loaded)
Mutant oncogene
Protein structure

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