Technical Articles

The Klotho protein is a product encoded by the anti-aging gene Klotho, which was discovered in 1997 in a salt-sensitive hypertensive mouse model. Both human and mouse Klotho genes are located on chromosome 13.

The α-Klotho protein serves as a crucial geroprotective factor, playing a pivotal role in counteracting oxidative stress, hypoxia, and cytotoxic damage. Scientific evidence demonstrates that this protein effectively mitigates deleterious alterations associated with aging and various pathological conditions.