Technical Articles
LGR5
R-Spondin 1(21-146) Protein: The "Super Amplifier" of the Wnt Pathway, A Revolutionary Tool in Regenerative Medicine and Disease Research
R-Spondin 1(21-146) is the core functional fragment of the R-Spondin 1 protein, a recombinant protein optimized through genetic engineering. It serves as a potent "catalyst" and "stabilizer" for the Wnt/β-catenin signaling pathway, playing an irreplaceable role in stem cell maintenance, tissue regeneration, and disease modeling.
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- Signaling Pathway
- R-Spondin 1(21-146)
- Recombinant Protein
- Wnt/β-catenin Signaling Pathway
- LGR5
R-Spondin 1(21-146): The "super-enhancer" of the Wnt pathway, its pivotal role in regenerative medicine and disease
R-Spondin 1(21-146) is the core active fragment of the R-Spondin 1 protein, designed to efficiently and stably amplify the Wnt signaling pathway. As a "catalyst" for tissue regeneration and stem cell maintenance, it plays a key role in intestinal health, sexual development, and disease models.
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- Signaling Pathway
- R-Spondin 1
- RSPO1(21-146)
- Wnt/β-catenin signaling pathway
- LGR5
- ZNRF3/RNF43
- Organoid.
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