Technical Articles

MHC-I molecular complex

非洲爪蟾肽-MHC-I分子复合体结构解析：揭示两栖类独特抗原结合机制及抗虹彩病毒免疫应答

Structural Elucidation of the Xenopus laevis Peptide-MHC-I Molecular Complex: Unveiling Amphibian-Specific Antigen-Binding Mechanisms and Anti-Iridovirus Immune Responses

2025-05-12

This study reports the first structural elucidation of the peptide-major histocompatibility complex class I (pMHC-I) molecular complex in Xenopus laevis, uncovering unique conformational features of antigen presentation in amphibians and structural mechanisms underlying resistance to iridovirus infection.

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Immunity/Inflamma
African clawed frog peptide
MHC-I molecular complex
Xenopus laevis

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