Technical Articles

Macrophage Polarization

New Mechanism of STAT6 Acetylation Modification in the Regulation of Tumor-Associated Macrophage Polarization

2026-01-30

In the tumor immune microenvironment, tumor-associated macrophages (TAMs) play a complex and critical role.

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Cancer
STAT6 His&Strep Tag protein
Tumor immune microenvironment
Macrophage polarization

Macrophage polarization cytokines: The "conductors" of the immune system, determining the ultimate balance between inflammation and repair

2025-12-02

Macrophage polarization is a core regulatory event in immune responses, with cytokines serving as the "chemical instructions" guiding this process.

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Immunity/Inflamma
Cytokines
Macrophage Polarization
Infection
Tumor
Autoimmune Disease

Precise Regulation of Macrophage Polarization: Deciphering the Pivotal Role of Cytokines in M1/M2 Phenotype Induction

2025-10-29

At the forefront of immunology research, macrophage plasticity and functional polarization have become central to understanding inflammation, tissue repair, and the tumor immune microenvironment. The precise in vitro differentiation of human monocytes into M1 (pro-inflammatory) or M2 (anti-inflammatory/repair) macrophages is a critical technology for simulating in vivo immune status, conducting drug screening, and facilitating cell therapy research.

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Cell Biology
Macrophage Polarization
M1/M2 Phenotypes
Cytokines
UA Bioscience

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