Technical Articles
Mutant oncogene
Application of KRAS G13D & VCB Binding Kit in Targeted Therapy
2026-03-06The KRAS gene is one of the most frequently mutated oncogenes in human cancers, appearing at high frequencies in pancreatic, colorectal, and lung cancers. As a central regulator of cellular signaling pathways, the KRAS protein functions like a molecular switch to control cell division and quiescence.
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- Cancer
- KRAS gene
- KRAS G13D
- Mutant oncogene
Application of KRAS G12V & VCB Binding Kit in Targeted Therapy
2026-03-06The KRAS gene is one of the most frequently mutated oncogenes in human malignancies, with this mutation detected in approximately one in seven cancers.
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- Cancer
- KRAS gene
- KRAS G12V
- Mutant oncogene
Application of Human KRAS G13D & VCB Binding Kit in KRAS-Targeted Therapy Research
2026-03-05The KRAS gene is one of the most frequently mutated oncogenes in human cancers, occurring in approximately 10-25% of non-small cell lung cancer cases and is closely associated with poor prognosis.
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- Cancer
- KRAS G13D
- Mutant oncogene
- Non-small cell lung cancer
Application of Human KRAS G12D & SOS1 Binding Assay Kit in Broad-Spectrum KRAS-Targeted Therapy Research
2026-03-04The KRAS gene, as one of the most frequently mutated oncogenes in human cancers, has long been considered an "undruggable" target due to its protein structural characteristics.
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- Drug Research
- KRAS G12D & SOS1 Binding Kit (GDP load)
- Mutant oncogene
- Non-small cell lung cancer
Research Progress on Resistance Mechanisms and Counterstrategies of KRAS G12C Inhibitors
2026-03-02The KRAS gene is one of the most frequently mutated oncogenes in cancer. Due to its protein structure lacking ideal drug-binding pockets and its extremely high affinity for GTP, KRAS mutations have long been considered an "undruggable" target.
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- Cancer
- KRAS G12C & CRBN Binding Kit (GDP loaded)
- Mutant oncogene
- Protein structure
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