Technical Articles

RAS is the most widely mutated oncogene in tumors, occurring in nearly 30% of human cancers. The RAS family includes three subtypes: KRAS, HRAS, and NRAS, with KRAS gene mutations accounting for approximately 85% of RAS family mutations.

The KRAS gene is one of the oncogenes frequently mutated in tumors, with the G12D mutation widely present in various malignant tumors such as pancreatic cancer, colorectal cancer, and lung cancer.