Technical Articles

Myeloid Malignancy
基于TR-FRET技术的BCL-xL靶向PROTAC降解剂在髓系恶性肿瘤中的研究
Study on BCL-xL-targeting PROTAC degraders based on TR-FRET technology in myeloid malignancies
发布时间 2026-04-16
Apoptosis is a tightly regulated programmed cell death process that enables cells to maintain tissue homeostasis and prevent tumorigenesis. The intrinsic mitochondrial pathway is activated by various stimuli, with BCL-2 family proteins playing a pivotal role in this pathway.
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  • Cancer
  • BCL-XL/CRBN
  • Myeloid Malignancy
  • Apoptosis
Total 1
  • 1
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