Technical Articles

Membranous nephropathy (MN) is a histological pattern characterized by glomerular injury, characterized by the deposition of electron dense material in the subcutaneous area above the glomerular basement membrane. It is one of the common causes of adult nephrotic syndrome. In the past decade, significant breakthroughs have been made in the study of the pathogenesis and exploration of treatment methods for MN. Up to now, researchers have identified more than ten related target antigens, among which neural cell adhesion molecule 1 (NCAM-1) is one of the important antigens that has attracted much attention, providing a new perspective for the etiology research and clinical diagnosis and treatment of MN.