Technical Articles
NLRP3 Inflammasome
IL-18: The "Igniter" of Inflammatory Storms, A Central Hub Linking Immune Defense and Chronic Diseases
2025-12-03Interleukin-18 (IL-18) is a key member of the IL-1 cytokine superfamily, renowned for its potent pro-inflammatory properties and ability to induce interferon-γ production. As a "pioneer signal" in immune responses, it serves as both a weapon against infections and a "culprit" driving numerous chronic inflammatory and autoimmune diseases.
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- Immunity/Inflamma
- IL-18
- Interleukin-18
- Inflammasome
- NLRP3 Inflammasome
- Cytokine Storm
IL-1β: The "Igniter" of Inflammation and a Key Driver of Systemic Diseases
2025-11-24IL-1β (Interleukin-1β) is one of the most potent pro-inflammatory cytokines in the body and is regarded as the "initiating factor" of inflammatory responses. Its production requires a precise and complex activation mechanism.
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- Immunity/Inflamma
- IL-1β
- interleukin-1β
- inflammasome
- NLRP3 inflammasome
- caspase-1
- autoinflammatory diseases
- gout.
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