Technical Articles

PDGF-AA is a unique homodimeric member of the platelet-derived growth factor family, renowned for its high-specificity affinity for the PDGFR-α receptor. As a potent mitogen and chemotactic factor, it plays a central role in embryonic development, tissue repair, and vascular homeostasis.

PDGF-AA is a key member of the platelet-derived growth factor family, serving as a critical signaling protein that plays a central role in cell growth, migration, and survival.

PDGF-AA (platelet-derived growth factor AA) is one of the key growth factors stored in platelet alpha granules and belongs to the PDGF family. In HPL, PDGF-AA plays a central role in regulating tissue repair and regeneration by promoting cell proliferation, migration, and synthesis of extracellular matrix.

PDGF-AA (a homodimer composed of two A subunits) has become a core functional molecule for PRP to promote wound healing and tissue regeneration due to its precise regulatory ability on mesenchymal cells (fibroblasts, mesenchymal stem cells, etc.). Its receptor binding properties and biological functions directly determine the repair efficiency of PRP