Technical Articles

Pancreatic ductal adenocarcinoma, known as the "king of cancers," is notorious for its high malignancy and extremely poor prognosis. The KRAS gene mutation occurs in up to 93% of pancreatic cancer cases, with KRAS G12D being the most common mutation subtype.

Pancreatic ductal adenocarcinoma is one of the most malignant tumors in the digestive system, with a 5-year survival rate consistently below 10%. KRAS gene mutation is the earliest and most common driving event in the development and progression of PDAC.