Technical Articles

Protein Degrader
基于TR-FRET技术的CRBN配体筛选在蛋白质降解剂研发中的应用
Application of CRBN Ligand Screening Based on TR-FRET Technology in the Development of Protein Degraders
发布时间 2026-04-13
Thalidomide is a compound composed of glutarimide and phthalimide, and its derivatives lenalidomide and pomalidomide are collectively known as immunomodulatory imide drugs, primarily used to treat hematologic malignancies such as multiple myeloma.
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  • Drug Research
  • TR-FRET Technology
  • CRBN Ligand
  • Protein Degrader
GSPT1蛋白降解剂的研发进展与DDB1-CRBN&GSPT1 PROTAC试剂盒的应用价值
Research Progress on GSPT1 Protein Degraders and the Application Value of DDB1-CRBN&GSPT1 PROTAC Reagent Kits
发布时间 2026-01-22
Targeted protein degradation (TPD) is a promising new direction in anticancer therapy, with molecular glues and PROTAC strategies demonstrating significant potential in inducing the degradation of disease-causing proteins.
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  • Cancer
  • DDB1-CRBN&GSPT1 PROTAC Kit
  • Malignant tumor
  • Protein degrader
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