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Protein structure
KRAS G12C抑制剂耐药机制及应对策略研究进展
Research Progress on Resistance Mechanisms and Counterstrategies of KRAS G12C Inhibitors
发布时间 2026-03-02
The KRAS gene is one of the most frequently mutated oncogenes in cancer. Due to its protein structure lacking ideal drug-binding pockets and its extremely high affinity for GTP, KRAS mutations have long been considered an "undruggable" target.
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  • Cancer
  • KRAS G12C & CRBN Binding Kit (GDP loaded)
  • Mutant oncogene
  • Protein structure
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  • 1
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