Technical Articles

Matrix metalloproteinase-9 (MMP-9, gelatinase B) is a member of the zinc-dependent endopeptidase family, capable of degrading various substrates in the extracellular matrix (ECM), including type IV collagen and gelatin.

Stem cell factor (SCF, also known as Kit ligand or mast cell growth factor) is a type I transmembrane protein, whose soluble form is produced by proteolytic cleavage and is the only known ligand for the c-Kit receptor (CD117).

Interleukin-21 receptor (IL-21R) is a member of the type I cytokine receptor family, forming a high-affinity heterodimeric receptor complex with the common gamma chain (γc) to mediate IL-21 signal transduction.

This article systematically introduces the molecular characteristics of recombinant GPX4 protein with dual Flag and His tags, its expression and purification strategies, as well as its key applications in elucidating the mechanisms of ferroptosis, screening inhibitors, and enzyme activity assays, providing core experimental materials for researchers in the fields of cell biology and drug development.

Noggin is a secreted glycoprotein and a key morphogen antagonist that regulates embryonic development and organ formation.

Furin/PCSK3 His Tag is a key protease tool protein expressed and purified through recombinant technology. Furin (also known as Proprotein Convertase 3 or PACE) is the most representative member of the proprotein convertase family, belonging to the calcium-dependent serine proteases.

BAFF&APRIL Heterotrimer His Tag is a uniquely designed recombinant cytokine complex, engineered to synergistically mimic and enhance the biological effects of two critical B-cell survival factors.

HRP-Labeled ATG4B His Tag is a recombinant protein tool that fuses the autophagy key enzyme ATG4B with horseradish peroxidase (HRP). As a "molecular probe" in the field of autophagy research, it does not directly cause diseases but serves as a critical reagent for studying the mechanisms of autophagy dysregulation in cancer, neurodegenerative diseases (such as Alzheimer's and Parkinson's), metabolic syndrome, and infectious diseases.

R-Spondin 1(21-146) is the core functional fragment of the R-Spondin 1 protein, a recombinant protein optimized through genetic engineering. It serves as a potent "catalyst" and "stabilizer" for the Wnt/β-catenin signaling pathway, playing an irreplaceable role in stem cell maintenance, tissue regeneration, and disease modeling.

Obtaining large numbers of highly active human peripheral blood-derived T cells is a critically important technical step in immunotherapy development, oncology research, and the exploration of immune response mechanisms. Traditional T cell expansion requires researchers to independently optimize the concentrations of anti-CD3 and anti-CD28 antibodies, as well as the ratio of IL-2 - a process that is cumbersome and involves variables that are difficult to control.