Technical Articles

Recombinant Protein Expert

TEAD3: The "invisible guardian" of bone health and the "brake valve" of tumor bone metastasis

2025-04-28

Targeting TEAD3 may be a 'master key' that can both strengthen the 'walls' of bones and cut off the 'escape channel' of tumor cells.

View details

Cancer
TEAD3
Bone Health
Nanjing Youai
Recombinant Protein Expert

SHPS1: The key "signal switch" for macrophages to regulate tumor immunity - from basic mechanisms to therapeutic breakthroughs

2025-04-28

SHPS1 (SHP substrate 1), also known as SIRPα (Signal Regulatory Protein α), is a member of the immunoglobulin superfamily and is mainly expressed on the surface of myeloid cells such as macrophages and dendritic cells. Its intracellular segment contains an immunoreceptor tyrosine inhibitory motif (ITIM), which can recruit tyrosine phosphatases SHP-1 and SHP-2 to regulate downstream signaling pathways.

View details

Cancer
SHPS1
Macrophage
Tumor
Recombinant Protein Expert
Nanjing Youai

Total 2

Go to