Technical Articles

SEK2 (SAPK/EKK kinase 2) is a pivotal kinase in the cellular stress response pathway, serving as the direct upstream activator of the JNK signaling pathway and playing a decisive role in cell survival, apoptosis, and inflammatory responses. This article will provide an in-depth analysis of the molecular characteristics of SEK2, comprehensively explore its central role in various pathological processes such as inflammatory diseases, neurodegenerative disorders, and cancer, and展望 its clinical application prospects in targeted therapy.