Technical Articles

In the field of cancer immunotherapy, SHP1 (Src homology region 2 protein tyrosine phosphatase-1) is gradually becoming a research focus. SHP1 is a non-receptor protein tyrosine phosphatase that is mainly expressed in hematopoietic cells and regulates cell signaling through dephosphorylation. It plays an important role in the immune system, regulating the proliferation, apoptosis, adhesion and signaling of B cells, T cells, myeloid cells and natural killer cells.