Technical Articles

T cells are core cells in the acquired immune system, responsible for recognizing antigens and initiating immune responses. T cell development is a complex process that is strictly regulated by the thymic microenvironment and signal transduction. In this process, tyrosine phosphorylation plays a vital role, and SHP1 (Src homology region 2 protein tyrosine phosphatase-1), as a key phosphatase, plays an important regulatory role in the development and function of T cells.