Technical Articles

Sepsis is one of the leading causes of hospital mortality, and its pathological mechanisms remain unclear. Currently, sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection.

Sepsis is one of the leading causes of death in intensive care units, with the core mechanism of its occurrence and development lying in immune dysfunction. Recent clinical studies have shown that a reduction in lymphocyte counts, including T lymphocytes, B lymphocytes, and dendritic cells, occurs during the early pro-inflammatory phase of sepsis.

Sepsis is a significant cause of patient mortality worldwide, with its complex pathophysiological process involving systemic inflammatory response and subsequent immune suppression.