Technical Articles

Siglec-2/CD22 Protein

Application of Siglec-2/CD22 Fc chimeric protein in targeted therapy for B-cell malignancies

2026-04-29

CD22 is a member of the sialic acid-binding immunoglobulin-type lectin family, a type I transmembrane protein that specifically binds to sialic acid-containing glycans and inhibits B-cell receptor signaling through its immunoreceptor tyrosine-based inhibitory motif, thereby maintaining humoral immune homeostasis.

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Cancer
Siglec-2/CD22 Protein
B Cells
Malignant Tumor

Total 1

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