Technical Articles

Solid Tumors

Application of FITC-labeled GUCY2C His-tagged protein in solid tumor immunotherapy research

2026-04-30

Guanylyl cyclase C is a transmembrane protein belonging to the receptor guanylyl cyclase family. It is activated by Escherichia coli heat-stable enterotoxin, guanylin, and uroguanylin, transmitting extracellular signals to the intracellular environment and participating in the regulation of intestinal function.

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Cancer
GUCY2C Protein
Solid Tumors
Immunotherapy

FITC标记的MSLN/Mesothelin Fc嵌合蛋白在实体瘤靶向治疗研究中的应用

Application of FITC-labeled MSLN/Mesothelin Fc chimeric protein in targeted therapy research for solid tumors

2026-04-28

The MSLN gene encodes a precursor protein that undergoes proteolytic processing to generate two protein products: megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor acts as a cytokine that stimulates the formation of megakaryocyte colonies in the bone marrow.

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Cancer
MSLN/Mesothelin
Solid Tumors
Signaling Pathway

Application of PE-labeled MSLN Fc and Avi-tagged proteins in solid tumor immunotherapy research

2026-04-27

Mesothelin is a glycosylphosphatidylinositol-anchored cell surface glycoprotein. The MSLN gene is located at 16p13.3 and encodes the MSLN precursor protein, which is proteolytically cleaved to yield two protein products: megakaryocyte potentiating factor and mesothelin.

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Cancer
MSLN Protein
Solid Tumors
Immunotherapy

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