Technical Articles

T cell receptor
ITK/CRBN轴：T细胞信号调控与靶向蛋白降解的分子工具
ITK/CRBN axis: Molecular tools for T-cell signaling regulation and targeted protein degradation
发布时间 2026-06-05
ITK is a core non-receptor tyrosine kinase in the T cell receptor signaling pathway, playing a regulatory role in T cell subset differentiation by controlling PLCγ1 activation and calcium signal intensity.
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  • Cancer
  • ITK
  • CRBN
  • PROTAC
  • T cell receptor
  • signaling pathway
Total 1
  • 1
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