Technical Articles

TNFR-1/CD120a:炎症与细胞死亡的"主开关",如何成为自身免疫病与癌症治疗的核心靶点
TNFR-1/CD120a: The "Master Switch" of Inflammation and Cell Death – How It Becomes a Core Target for Autoimmune Disease and Cancer Therapy
发布时间 2025-11-25
TNFR-1, also known as CD120a, is one of the most important receptors for tumor necrosis factor. It serves as a "master switch" for inflammation and cell death programs, playing a central role in immune defense, tissue homeostasis, and disease development.
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  • Immunity/Inflamma
  • TNFR-1
  • Cancer treatment
  • Autoimmune diseases
  • Cytokine.
TNFR-1/CD120a:从炎症信号传导到靶向治疗的关键受体
TNFR-1/CD10a: Key receptors from inflammatory signaling to targeted therapy
发布时间 2025-08-27
TNFR-1, Also known as CD120a or TNFRSF1A, it is a member of the tumor necrosis factor receptor superfamily, primarily responsible for mediating the biological functions of TNF - α. As a type I transmembrane protein widely expressed on various cell surfaces, TNFR-1 plays a central role in key immune processes such as inflammation, cell survival, and programmed cell death.
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  • Immunity/Inflamma
  • TNFR-1
  • CD120a
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