Technical Articles
TNFR-1
TNFR-1/CD120a: The "Master Switch" of Inflammation and Cell Death – How It Becomes a Core Target for Autoimmune Disease and Cancer Therapy
TNFR-1, also known as CD120a, is one of the most important receptors for tumor necrosis factor. It serves as a "master switch" for inflammation and cell death programs, playing a central role in immune defense, tissue homeostasis, and disease development.
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- Immunity/Inflamma
- TNFR-1
- Cancer treatment
- Autoimmune diseases
- Cytokine.
TNFR-1/CD10a: Key receptors from inflammatory signaling to targeted therapy
TNFR-1, Also known as CD120a or TNFRSF1A, it is a member of the tumor necrosis factor receptor superfamily, primarily responsible for mediating the biological functions of TNF - α. As a type I transmembrane protein widely expressed on various cell surfaces, TNFR-1 plays a central role in key immune processes such as inflammation, cell survival, and programmed cell death.
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- Immunity/Inflamma
- TNFR-1
- CD120a
- 1












