Technical Articles

Th17 cells are a subset of CD4+ T cells characterized by the secretion of IL-17A as their signature effector molecule, and their differentiation is regulated by the transcription factor RORγt. Th17 cells play a critical role in autoimmune diseases and inflammatory disorders, while also maintaining important functions in intestinal mucosal homeostasis.

CD4+辅助性T细胞是适应性免疫应答的核心调节细胞，根据分化方向不同可分为多个功能亚群。其中Th17细胞因其在自身免疫性疾病和宿主防御中的独特作用，成为免疫学研究的热点。